Staff View: Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia

Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia

INTRODUCTION: Serum uric acid has been considered a marker or an element of the clinical and laboratory alterations in the metabolic syndrome. OBJECTIVE: to evaluate the association between levels of serum uric acid (UA) and the following laboratory profile: fasting glucose > 100 mg/dl, triglycer...

Full description

Main Authors:	Rosa, Tânia Torres, Moura, Ewandro Luiz Rey, Oliveira, Manuela Costa de, Boff, Gláucia, Junqueira Junior, Luiz Fernando, Veiga, Joel Paulo Russomano
Format:	Artigo
Language:	English
Published:	Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia 2017
Subjects:	Ambulatory subjects Hyperuricemia Hyperglycemia Dyslipidemia Pacientes ambulatoriais Hiperuricemia Hiperglicemia Dislipidemia
Online Access:	http://repositorio.unb.br/handle/10482/27890
Tags:	Add Tag No Tags, Be the first to tag this record!

id	ir-10482-27890
recordtype	dspace
spelling	ir-10482-278902019-03-28T14:02:25Z Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia A prevalência de hiperuricemia está aumentada em pacientes ambulatoriais com hiperglicemia e dislipidemia Rosa, Tânia Torres Moura, Ewandro Luiz Rey Oliveira, Manuela Costa de Boff, Gláucia Junqueira Junior, Luiz Fernando Veiga, Joel Paulo Russomano Ambulatory subjects Hyperuricemia Hyperglycemia Dyslipidemia Pacientes ambulatoriais Hiperuricemia Hiperglicemia Dislipidemia INTRODUCTION: Serum uric acid has been considered a marker or an element of the clinical and laboratory alterations in the metabolic syndrome. OBJECTIVE: to evaluate the association between levels of serum uric acid (UA) and the following laboratory profile: fasting glucose > 100 mg/dl, triglycerides > 150 mg/dl and high density lipoprotein cholesterol (HDL-C) < 50 mg/dl in women and < 40 mg/dl in men. METHOD: In a cross-sectional survey, blood samples of 4,328 randomized outpatients aged from 20 to 102 years were analyzed. RESULTS: The mean (interquartile range) UA level was higher in men (6.7; 2.4-12.5 mg/dl) and women (5.4; 2.0-12.2 mg/dl) with the laboratorial profile than in those without it (5.9; 0.90-33.8 mg/dl for men and 4.4; 0.8-30.0 mg/dl for women) (p < 0.0001). A significant increase in the prevalence of laboratory profile was observed in men (OR = 2.2 mg/dl; 95% CI: 1.2-3.9 mg/dl) and women (OR = 2.2 mg/dl; 95% CI: 1.4-3.5 mg/dl) with hyperuricemia. CONCLUSION: These results show the association between serum levels of uric acid and metabolic syndrome profile, which corroborates to similar results found in other populations worldwide. INTRODUÇÃO: O ácido úrico sérico tem sido considerado um marcador ou componente das alterações clínicas e laboratoriais da síndrome metabólica. OBJETIVO: Avaliar a associação entre o ácido úrico sérico (AU) e o perfil laboratorial composto de glicemia de jejum > 100 mg/dl, triglicerídeos > 150 mg/dl e colesterol da lipoproteína de alta densidade (HDL-C) < 50 mg/dl nas mulheres e < 40 mg/dl nos homens. MÉTODO: Em estudo de corte transversal, amostras de sangue de 4.328 pacientes ambulatoriais não selecionados com idade variando de 20 a 102 anos foram examinadas. RESULTADOS: A mediana (variação interquartil) do AU foi mais elevada nos homens (6,7; 2,4-12,5 mg/dl) e mulheres (5,4;2-12,2 mg/dl) que apresentaram o perfil laboratorial do que nos que não o apresentaram (5,9; 0,9-33,8 mg/dl para os homens e 4,4; 0,8-30 mg/dl para as mulheres) (p < 0,0001). Observou-se aumento significativo na prevalência do perfil laboratorial nos homens (razão de chance [RC] = 2,2 mg/dl; intervalo de confiança [IC] 95%: 1,2-3,9 mg/dl) e mulheres (RC = 2,2 mg/dl; IC 95%: 1,4-3,5 mg/dl) com hiperuricemia. CONCLUSÃO: Esses resultados mostram a associação dos níveis séricos do acido úrico com o perfil laboratorial da síndrome metabólica nesse grupo não selecionado de indivíduos brasileiros atendidos ambulatorialmente, sendo este um achado semelhante ao observado em outras populações estudadas mundialmente. 2017-12-07T04:55:18Z 2017-12-07T04:55:18Z 2010 Artigo J. Bras. Patol. Med. Lab.,v.46,n.4,p.283-288,2010 1676-2444 http://repositorio.unb.br/handle/10482/27890 10.1590/S1676-24442010000400004 en Acesso Aberto application/pdf Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442010000400004&lng=en&nrm=iso http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1676-24442010000400004&lng=en&nrm=iso http://www.scielo.br/scielo.php?script=sci_pdf&pid=S1676-24442010000400004&lng=en&nrm=iso
institution	REPOSITORIO UNB
collection	REPOSITORIO UNB
language	English
topic	Ambulatory subjects Hyperuricemia Hyperglycemia Dyslipidemia Pacientes ambulatoriais Hiperuricemia Hiperglicemia Dislipidemia
spellingShingle	Ambulatory subjects Hyperuricemia Hyperglycemia Dyslipidemia Pacientes ambulatoriais Hiperuricemia Hiperglicemia Dislipidemia Rosa, Tânia Torres Moura, Ewandro Luiz Rey Oliveira, Manuela Costa de Boff, Gláucia Junqueira Junior, Luiz Fernando Veiga, Joel Paulo Russomano Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia
description	INTRODUCTION: Serum uric acid has been considered a marker or an element of the clinical and laboratory alterations in the metabolic syndrome. OBJECTIVE: to evaluate the association between levels of serum uric acid (UA) and the following laboratory profile: fasting glucose > 100 mg/dl, triglycerides > 150 mg/dl and high density lipoprotein cholesterol (HDL-C) < 50 mg/dl in women and < 40 mg/dl in men. METHOD: In a cross-sectional survey, blood samples of 4,328 randomized outpatients aged from 20 to 102 years were analyzed. RESULTS: The mean (interquartile range) UA level was higher in men (6.7; 2.4-12.5 mg/dl) and women (5.4; 2.0-12.2 mg/dl) with the laboratorial profile than in those without it (5.9; 0.90-33.8 mg/dl for men and 4.4; 0.8-30.0 mg/dl for women) (p < 0.0001). A significant increase in the prevalence of laboratory profile was observed in men (OR = 2.2 mg/dl; 95% CI: 1.2-3.9 mg/dl) and women (OR = 2.2 mg/dl; 95% CI: 1.4-3.5 mg/dl) with hyperuricemia. CONCLUSION: These results show the association between serum levels of uric acid and metabolic syndrome profile, which corroborates to similar results found in other populations worldwide.
format	Artigo
author	Rosa, Tânia Torres Moura, Ewandro Luiz Rey Oliveira, Manuela Costa de Boff, Gláucia Junqueira Junior, Luiz Fernando Veiga, Joel Paulo Russomano
author_sort	Rosa, Tânia Torres
title	Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia
title_short	Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia
title_full	Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia
title_fullStr	Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia
title_full_unstemmed	Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia
title_sort	prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia
publisher	Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia
publishDate	2017
url	http://repositorio.unb.br/handle/10482/27890
_version_	1641988708174397440
score	13.657419

Prevalence of high serum uric acid is increased in ambulatory subjects with hyperglycemia and dyslipidemia

Similar Items