Staff View: Complementary exams in the diagnosis of american tegumentary leishmaniasis

Complementary exams in the diagnosis of american tegumentary leishmaniasis

The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as t...

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Main Authors:	Gomes, Ciro Martins, Paula, Natália Aparecida de, Morais, Orlando Oliveira de, Soares, Killarney Ataíde, Roselino, Ana Maria, Sampaio, Raimunda Nonata Ribeiro
Format:	Artigo
Language:	English
Published:	Sociedade Brasileira de Dermatologia 2017
Subjects:	Dermatologia Diagnóstico Leishmaniose mucocutânea Biologia molecular Reação em cadeia de polimerase Sorologia
Online Access:	http://repositorio.unb.br/handle/10482/29295 https://dx.doi.org/10.1590/abd1806-4841.20142389
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spelling	ir-10482-292952019-12-16T15:08:43Z Complementary exams in the diagnosis of american tegumentary leishmaniasis Gomes, Ciro Martins Paula, Natália Aparecida de Morais, Orlando Oliveira de Soares, Killarney Ataíde Roselino, Ana Maria Sampaio, Raimunda Nonata Ribeiro Dermatologia Diagnóstico Leishmaniose mucocutânea Biologia molecular Reação em cadeia de polimerase Sorologia The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as the gold standard, since they do not add enough accuracy for the disease detection. Good epidemiological and clinical knowledge of the disease are fundamental precepts of the dermatology practice and precede the rational use of existing diagnostic tests. In this article we aim, through extensive literature review, to recall fundamental concepts of any diagnostic test. Subsequently, based on this information, we will weave important comments about the characteristics of existing diagnostic tests, including immunological tests such as Montenegro's skin test, serology and detection of parasites by direct examination, culture or histopathology. Finally we will discuss the new technologies and options for the diagnosis of Cutaneous Leishmaniasis. The molecular biology technique is considered a promising tool, promoting the rapid identification of the species involved. We also aim to educate dermatologists about a disease with high morbidity and assist in its difficult recognition. 2017-12-07T05:07:32Z 2017-12-07T05:07:32Z 2014 Artigo GOMES, Ciro Martins et al. Complementary exams in the diagnosis of american tegumentary leishmaniasis. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 89, n. 5, p. 701-709, out. 2014. DOI: http://dx.doi.org/10.1590/abd1806-4841.20142389. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&nrm=iso. Acesso em: 08 dez. 2019. http://repositorio.unb.br/handle/10482/29295 https://dx.doi.org/10.1590/abd1806-4841.20142389 en Acesso Aberto Anais Brasileiros de Dermatologia - (CC BY NC) - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&tlng=en. Acesso em: 08 dez. 2019. application/pdf Sociedade Brasileira de Dermatologia
institution	REPOSITORIO UNB
collection	REPOSITORIO UNB
language	English
topic	Dermatologia Diagnóstico Leishmaniose mucocutânea Biologia molecular Reação em cadeia de polimerase Sorologia
spellingShingle	Dermatologia Diagnóstico Leishmaniose mucocutânea Biologia molecular Reação em cadeia de polimerase Sorologia Gomes, Ciro Martins Paula, Natália Aparecida de Morais, Orlando Oliveira de Soares, Killarney Ataíde Roselino, Ana Maria Sampaio, Raimunda Nonata Ribeiro Complementary exams in the diagnosis of american tegumentary leishmaniasis
description	The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as the gold standard, since they do not add enough accuracy for the disease detection. Good epidemiological and clinical knowledge of the disease are fundamental precepts of the dermatology practice and precede the rational use of existing diagnostic tests. In this article we aim, through extensive literature review, to recall fundamental concepts of any diagnostic test. Subsequently, based on this information, we will weave important comments about the characteristics of existing diagnostic tests, including immunological tests such as Montenegro's skin test, serology and detection of parasites by direct examination, culture or histopathology. Finally we will discuss the new technologies and options for the diagnosis of Cutaneous Leishmaniasis. The molecular biology technique is considered a promising tool, promoting the rapid identification of the species involved. We also aim to educate dermatologists about a disease with high morbidity and assist in its difficult recognition.
format	Artigo
author	Gomes, Ciro Martins Paula, Natália Aparecida de Morais, Orlando Oliveira de Soares, Killarney Ataíde Roselino, Ana Maria Sampaio, Raimunda Nonata Ribeiro
author_sort	Gomes, Ciro Martins
title	Complementary exams in the diagnosis of american tegumentary leishmaniasis
title_short	Complementary exams in the diagnosis of american tegumentary leishmaniasis
title_full	Complementary exams in the diagnosis of american tegumentary leishmaniasis
title_fullStr	Complementary exams in the diagnosis of american tegumentary leishmaniasis
title_full_unstemmed	Complementary exams in the diagnosis of american tegumentary leishmaniasis
title_sort	complementary exams in the diagnosis of american tegumentary leishmaniasis
publisher	Sociedade Brasileira de Dermatologia
publishDate	2017
url	http://repositorio.unb.br/handle/10482/29295 https://dx.doi.org/10.1590/abd1806-4841.20142389
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score	13.657419

Complementary exams in the diagnosis of american tegumentary leishmaniasis

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