Staff View: Leishmania (Viannia) naiffi : rare enough to be neglected?

Leishmania (Viannia) naiffi : rare enough to be neglected?

In the Brazilian Amazon, American tegumentary leishmaniasis (ATL) is endemic and presents a wide spectrum of clinical manifestations due, in part, to the circulation of at least seven Leishmaniaspecies. Few reports of Leishmania (Viannia) naiffiinfection suggest that its occurrence is uncommon and t...

Full description

Main Authors:	Silva, Giselle Aparecida Fagundes, Romero, Gustavo Adolfo Sierra, Cupolillo, Elisa, Yamashita, Ellen Priscila Gadelha, Silva, Adriano Gomes, Guerra, Jorge Augusto de Oliveira, Cruz, Alda Maria da
Format:	Artigo
Language:	English
Published:	Instituto Oswaldo Cruz, Ministério da Saúde 2017
Subjects:	Enzimas Amazônia Leishmaniose
Online Access:	http://repositorio.unb.br/handle/10482/29539 http://dx.doi.org/10.1590/0074-02760150128
Tags:	Add Tag No Tags, Be the first to tag this record!

id	ir-10482-29539
recordtype	dspace
spelling	ir-10482-295392018-12-17T15:46:34Z Leishmania (Viannia) naiffi : rare enough to be neglected? Silva, Giselle Aparecida Fagundes Romero, Gustavo Adolfo Sierra Cupolillo, Elisa Yamashita, Ellen Priscila Gadelha Silva, Adriano Gomes Guerra, Jorge Augusto de Oliveira Cruz, Alda Maria da Enzimas Amazônia Leishmaniose In the Brazilian Amazon, American tegumentary leishmaniasis (ATL) is endemic and presents a wide spectrum of clinical manifestations due, in part, to the circulation of at least seven Leishmaniaspecies. Few reports of Leishmania (Viannia) naiffiinfection suggest that its occurrence is uncommon and the reported cases present a benign clinical course and a good response to treatment. This study aimed to strengthen the clinical and epidemiological importance of L. (V.) naiffiin the Amazon Region (Manaus, state of Amazonas) and to report therapeutic failure in patients infected with this species. Thirty Leishmania spp samples isolated from cutaneous lesions were characterised by multilocus enzyme electrophoresis. As expected, the most common species was Leishmania (V.) guyanensis (20 cases). However, a relevant number ofL. (V.) naiffi patients (8 cases) was observed, thus demonstrating that this species is not uncommon in the region. No patient infected withL. (V.) naiffievolved to spontaneous cure until the start of treatment, which indicated that this species may not have a self-limiting nature. In addition, two of the patients experienced a poor response to antimonial or pentamidine therapy. Thus, either ATL cases due to L. (V.) naifficannot be as uncommon as previously thought or this species is currently expanding in this region. 2017-12-07T05:11:37Z 2017-12-07T05:11:37Z 2015-09 Artigo FAGUNDES-SILVA, Giselle Aparecida et al. Leishmania (Viannia) naiffi: rare enough to be neglected? Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 110, n. 6, p. 797-800, set. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000600797&lng=en&nrm=iso>. Acesso em: 9 maio 2018. doi: http://dx.doi.org/10.1590/0074-02760150128. http://repositorio.unb.br/handle/10482/29539 http://dx.doi.org/10.1590/0074-02760150128 en Acesso Aberto Memórias do Instituto Oswaldo Cruz - This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000600797&lng=en&nrm=iso. Acesso em: 9 maio 2018. application/pdf Instituto Oswaldo Cruz, Ministério da Saúde
institution	REPOSITORIO UNB
collection	REPOSITORIO UNB
language	English
topic	Enzimas Amazônia Leishmaniose
spellingShingle	Enzimas Amazônia Leishmaniose Silva, Giselle Aparecida Fagundes Romero, Gustavo Adolfo Sierra Cupolillo, Elisa Yamashita, Ellen Priscila Gadelha Silva, Adriano Gomes Guerra, Jorge Augusto de Oliveira Cruz, Alda Maria da Leishmania (Viannia) naiffi : rare enough to be neglected?
description	In the Brazilian Amazon, American tegumentary leishmaniasis (ATL) is endemic and presents a wide spectrum of clinical manifestations due, in part, to the circulation of at least seven Leishmaniaspecies. Few reports of Leishmania (Viannia) naiffiinfection suggest that its occurrence is uncommon and the reported cases present a benign clinical course and a good response to treatment. This study aimed to strengthen the clinical and epidemiological importance of L. (V.) naiffiin the Amazon Region (Manaus, state of Amazonas) and to report therapeutic failure in patients infected with this species. Thirty Leishmania spp samples isolated from cutaneous lesions were characterised by multilocus enzyme electrophoresis. As expected, the most common species was Leishmania (V.) guyanensis (20 cases). However, a relevant number ofL. (V.) naiffi patients (8 cases) was observed, thus demonstrating that this species is not uncommon in the region. No patient infected withL. (V.) naiffievolved to spontaneous cure until the start of treatment, which indicated that this species may not have a self-limiting nature. In addition, two of the patients experienced a poor response to antimonial or pentamidine therapy. Thus, either ATL cases due to L. (V.) naifficannot be as uncommon as previously thought or this species is currently expanding in this region.
format	Artigo
author	Silva, Giselle Aparecida Fagundes Romero, Gustavo Adolfo Sierra Cupolillo, Elisa Yamashita, Ellen Priscila Gadelha Silva, Adriano Gomes Guerra, Jorge Augusto de Oliveira Cruz, Alda Maria da
author_sort	Silva, Giselle Aparecida Fagundes
title	Leishmania (Viannia) naiffi : rare enough to be neglected?
title_short	Leishmania (Viannia) naiffi : rare enough to be neglected?
title_full	Leishmania (Viannia) naiffi : rare enough to be neglected?
title_fullStr	Leishmania (Viannia) naiffi : rare enough to be neglected?
title_full_unstemmed	Leishmania (Viannia) naiffi : rare enough to be neglected?
title_sort	leishmania (viannia) naiffi : rare enough to be neglected?
publisher	Instituto Oswaldo Cruz, Ministério da Saúde
publishDate	2017
url	http://repositorio.unb.br/handle/10482/29539 http://dx.doi.org/10.1590/0074-02760150128
_version_	1641988138907729920
score	13.657419

Leishmania (Viannia) naiffi : rare enough to be neglected?

Similar Items