Brazilian Federal District cocaine chemical profiling : mass balance approach and new adulterant routinely quantified (Aminopyrine)
From a set of 159 samples seized by Brazilian Federal police between 2010 to 2013 in the Federal District, the major component chemical profiling routine analyses revealed the presence of cocaine with purity range of 5.5 to 99.9% (mean 69.8%). Most cocaine base samples show moderately and not oxidiz...
| Main Authors: | Maldaner, Adriano Otávio, Botelho, Élvio Dias, Zacca, Jorge Jardim, Camargo, Marcos A., Braga, Jez Willian Batista, Grobério, Tatiane Souza |
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Sociedade Brasileira de Química
2017
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ir-10482-296902019-08-13T15:15:15Z Brazilian Federal District cocaine chemical profiling : mass balance approach and new adulterant routinely quantified (Aminopyrine) Maldaner, Adriano Otávio Botelho, Élvio Dias Zacca, Jorge Jardim Camargo, Marcos A. Braga, Jez Willian Batista Grobério, Tatiane Souza Química - pesquisa Cocaína Balanço de massa From a set of 159 samples seized by Brazilian Federal police between 2010 to 2013 in the Federal District, the major component chemical profiling routine analyses revealed the presence of cocaine with purity range of 5.5 to 99.9% (mean 69.8%). Most cocaine base samples show moderately and not oxidized levels, whereas cocaine hydrochloride samples exhibit moderate to high oxidation degrees. More than 40% of the analyzed samples did not have any adulterant. Phenacetin was the most abundant adulterant (24% average purity). Aminopyrine, a new adulterant, was identified and quantified only in cocaine base samples, mainly as a trace adulterant but also as a major compound. In most samples adulterated with aminopyrine, phenacetin was also identified as a major adulterant, suggesting a possible association of the two pharmaceuticals in the cutting process. Aminopyrine was not detected in 2010 seizures, but became a common adulterant throughout the years of 2011 to 2013. A mass balance approach analysis also established that adulterants are responsible for only 12% of the mass of all seizures (i.e., 84 kg), whereas 77% (i.e., 553 kg) is due to alkaloids (cocaine and cis/trans-cinnamoylcocaine), contributing to provide forensic intelligence information to police investigators. 2017-12-07T05:12:54Z 2017-12-07T05:12:54Z 2015-06 Artigo MALDANER, Adriano Otávio et al. Brazilian Federal District cocaine chemical profiling: mass balance spproach and new adulterant routinely quantified (Aminopyrine). Journal of the Brazilian Chemical Society, São Paulo, v. 26, n. 6, p. 1227-1231, jun. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000601227&lng=en&nrm=iso>. Acesso em: 16 abr. 2018. doi: http://dx.doi.org/10.5935/0103-5053.20150088. http://repositorio.unb.br/handle/10482/29690 http://dx.doi.org/10.5935/0103-5053.20150088 en Acesso Aberto Journal of the Brazilian Chemical Society - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited (CC BY NC 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000601227&lng=en&nrm=iso. Acesso em: 16 abr. 2018. application/pdf Sociedade Brasileira de Química |
| institution |
REPOSITORIO UNB |
| collection |
REPOSITORIO UNB |
| language |
English |
| topic |
Química - pesquisa Cocaína Balanço de massa |
| spellingShingle |
Química - pesquisa Cocaína Balanço de massa Maldaner, Adriano Otávio Botelho, Élvio Dias Zacca, Jorge Jardim Camargo, Marcos A. Braga, Jez Willian Batista Grobério, Tatiane Souza Brazilian Federal District cocaine chemical profiling : mass balance approach and new adulterant routinely quantified (Aminopyrine) |
| description |
From a set of 159 samples seized by Brazilian Federal police between 2010 to 2013 in the Federal District, the major component chemical profiling routine analyses revealed the presence of cocaine with purity range of 5.5 to 99.9% (mean 69.8%). Most cocaine base samples show moderately and not oxidized levels, whereas cocaine hydrochloride samples exhibit moderate to high oxidation degrees. More than 40% of the analyzed samples did not have any adulterant. Phenacetin was the most abundant adulterant (24% average purity). Aminopyrine, a new adulterant, was identified and quantified only in cocaine base samples, mainly as a trace adulterant but also as a major compound. In most samples adulterated with aminopyrine, phenacetin was also identified as a major adulterant, suggesting a possible association of the two pharmaceuticals in the cutting process. Aminopyrine was not detected in 2010 seizures, but became a common adulterant throughout the years of 2011 to 2013. A mass balance approach analysis also established that adulterants are responsible for only 12% of the mass of all seizures (i.e., 84 kg), whereas 77% (i.e., 553 kg) is due to alkaloids (cocaine and cis/trans-cinnamoylcocaine), contributing to provide forensic intelligence information to police investigators. |
| format |
Artigo |
| author |
Maldaner, Adriano Otávio Botelho, Élvio Dias Zacca, Jorge Jardim Camargo, Marcos A. Braga, Jez Willian Batista Grobério, Tatiane Souza |
| author_sort |
Maldaner, Adriano Otávio |
| title |
Brazilian Federal District cocaine chemical profiling : mass balance approach and new adulterant routinely quantified (Aminopyrine) |
| title_short |
Brazilian Federal District cocaine chemical profiling : mass balance approach and new adulterant routinely quantified (Aminopyrine) |
| title_full |
Brazilian Federal District cocaine chemical profiling : mass balance approach and new adulterant routinely quantified (Aminopyrine) |
| title_fullStr |
Brazilian Federal District cocaine chemical profiling : mass balance approach and new adulterant routinely quantified (Aminopyrine) |
| title_full_unstemmed |
Brazilian Federal District cocaine chemical profiling : mass balance approach and new adulterant routinely quantified (Aminopyrine) |
| title_sort |
brazilian federal district cocaine chemical profiling : mass balance approach and new adulterant routinely quantified (aminopyrine) |
| publisher |
Sociedade Brasileira de Química |
| publishDate |
2017 |
| url |
http://repositorio.unb.br/handle/10482/29690 http://dx.doi.org/10.5935/0103-5053.20150088 |
| _version_ |
1642398392400216064 |
| score |
13.657419 |