ADME studies and preliminary safety pharmacology of LDT5, a lead compound for the treatment of benign prostatic hyperplasia

This study aimed to estimate the absorption, distribution, metabolism and excretion (ADME) properties and safety of LDT5, a lead compound for oral treatment of benign prostatic hyperplasia that has previously been characterized as a multi-target antagonist of α1A-, α1D-adrenoceptors and 5-HT1A recep...

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Main Authors: Noël, F., Nascimento-Viana, J.B., Romeiro, L.A.S., Silva, R.O., Lemes, L.F.N., Oliveira, A.S., Giorno, T.B.S., Fernandes, P.D., Silva, C.L.M.
Format: Artigo
Language: English
Published: Associação Brasileira de Divulgação Científica 2017
Subjects:
Online Access: http://repositorio.unb.br/handle/10482/30084
http://dx.doi.org/10.1590/1414-431x20165542
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