Simvastatin and biphasic calcium phosphate affects bone formation in critical-sized rat calvarial defects

Purpose: to investigate the effects of locally applied simvastatin plus biphasic calcium phosphate (BoneCeramic(r)) or collagen sponge on bone formation in critical-sized bone defects. Methods: thirty defects of 5mm in diameter were created bilaterally with a trephine bur in the calvariae of fifteen...

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Main Authors: Santana, Washington Macedo de, Sousa, Dircilei Nascimento de, Ferreira, Vania Maria Moraes, Duarte, Wagner Rodrigues
Format: Artigo
Language: English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2017
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Online Access: http://repositorio.unb.br/handle/10482/30182
http://dx.doi.org/10.1590/S0102-865020160050000002
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