Simvastatin and biphasic calcium phosphate affects bone formation in critical-sized rat calvarial defects
Purpose: to investigate the effects of locally applied simvastatin plus biphasic calcium phosphate (BoneCeramic(r)) or collagen sponge on bone formation in critical-sized bone defects. Methods: thirty defects of 5mm in diameter were created bilaterally with a trephine bur in the calvariae of fifteen...
Main Authors: | Santana, Washington Macedo de, Sousa, Dircilei Nascimento de, Ferreira, Vania Maria Moraes, Duarte, Wagner Rodrigues |
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Format: | Artigo |
Language: | English |
Published: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2017
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Subjects: | |
Online Access: |
http://repositorio.unb.br/handle/10482/30182 http://dx.doi.org/10.1590/S0102-865020160050000002 |
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