In vitro Anti-HMPV activity of new synthetic phenytoin derivatives

New derivatives of synthetic 5,5-diphenylhydantoin (phenytoin) were prepared by N-alkylation with 1,3-dibromopropane. Subsequent treatment with sodium azide led to the respective azide. Reaction of the azide with phenylacetylene and 2-hydroxy-3-butyne and oxidation of the resulting alcohol with MnO2...

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Main Authors: Mendes, Gabriella, Aspesi, Geisa H., Arruda, Ana L. A., Romanos, Maria T. V., Andrade, Carlos K. Z.
Format: Artigo
Language: English
Published: Sociedade Brasileira de Química 2017
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Online Access: http://repositorio.unb.br/handle/10482/30221
http://dx.doi.org/10.5935/0103-5053.20150234
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