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Ultraviolet index : a light in atopic dermatitis and vitamin D research?

The role played by vitamin D in atopic dermatitis is controversial and has been the focus of many studies. The ultraviolet index has not been considered in this type of research. OBJECTIVES: The objectives of the study were to assess 25-hydroxy vitamin D [25(OH)D] serum level in atopic dermatitis pa...

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Main Authors: Mesquita, Kleyton de Carvalho, Igreja, Ana Carolina de Souza Machado, Costa, Izelda Maria Carvalho
Format: Artigo
Language: English
Published: Sociedade Brasileira de Dermatologia 2017
Subjects:
Dermatite atópica
Radiação ultravioleta
Vitamina D
Online Access: http://repositorio.unb.br/handle/10482/30278
http://dx.doi.org/10.1590/abd1806-4841.20164337
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spelling ir-10482-302782018-10-03T14:47:09Z Ultraviolet index : a light in atopic dermatitis and vitamin D research? Mesquita, Kleyton de Carvalho Igreja, Ana Carolina de Souza Machado Costa, Izelda Maria Carvalho Dermatite atópica Radiação ultravioleta Vitamina D The role played by vitamin D in atopic dermatitis is controversial and has been the focus of many studies. The ultraviolet index has not been considered in this type of research. OBJECTIVES: The objectives of the study were to assess 25-hydroxy vitamin D [25(OH)D] serum level in atopic dermatitis patients and control group, to investigate the association between atopic dermatitis clinical severity (using the SCORing Atopic Dermatitis index - SCORAD) and 25(OH)D serum levels, and to evaluate the independent predictors, including Ultraviolet index, SCORAD and 25(OH)D. METHODS: We conducted a cross-sectional study of 106 atopic dermatitis patients. A control group was matched with a subsample of 54 participants with atopic dermatitis. SCORAD index, laboratory tests, and local Ultraviolet index were assessed. RESULTS: The atopic dermatitis patients had serum 25(OH)D levels and mean UVI significantly higher than the control group. Immunoglobulin E and Ultraviolet index were associated with the SCORAD index. Skin type, age and Ultraviolet index were independent predictors of 25(OH)D. CONCLUSIONS: Although statistically significant, the different levels of 25(OH)D between the paired groups may be attributed to the higher mean Ultraviolet index in atopic dermatitis patients. Since Ultraviolet index is an independent predictor of SCORAD index and of 25(OH)D level, it may work as a confounding factor in studies involving atopic dermatitis and 25(OH)D and must be considered in this kind of research. 2017-12-07T05:18:35Z 2017-12-07T05:18:35Z 2016-01 Artigo MESQUITA, Kleyton de Carvalho; IGREJA, Ana Carolina de Souza Machado; COSTA, Izelda Maria Carvalho. Ultraviolet index: a light in atopic dermatitis and vitamin D research? Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 91, n. 1, p. 34-39, jan./fev. 2016. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000100034&lng=en&nrm=iso>. Acesso em: 4 jan. 2018. doi: http://dx.doi.org/10.1590/abd1806-4841.20164337. http://repositorio.unb.br/handle/10482/30278 http://dx.doi.org/10.1590/abd1806-4841.20164337 en Acesso Aberto Anais Brasileiros de Dermatologia - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited (CC BY NC 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000100034&lng=en&nrm=iso. Acesso em: 4 jan. 2018. application/pdf Sociedade Brasileira de Dermatologia
institution REPOSITORIO UNB
collection REPOSITORIO UNB
language English
topic Dermatite atópica
Radiação ultravioleta
Vitamina D
spellingShingle Dermatite atópica
Radiação ultravioleta
Vitamina D
Mesquita, Kleyton de Carvalho
Igreja, Ana Carolina de Souza Machado
Costa, Izelda Maria Carvalho
Ultraviolet index : a light in atopic dermatitis and vitamin D research?
description The role played by vitamin D in atopic dermatitis is controversial and has been the focus of many studies. The ultraviolet index has not been considered in this type of research. OBJECTIVES: The objectives of the study were to assess 25-hydroxy vitamin D [25(OH)D] serum level in atopic dermatitis patients and control group, to investigate the association between atopic dermatitis clinical severity (using the SCORing Atopic Dermatitis index - SCORAD) and 25(OH)D serum levels, and to evaluate the independent predictors, including Ultraviolet index, SCORAD and 25(OH)D. METHODS: We conducted a cross-sectional study of 106 atopic dermatitis patients. A control group was matched with a subsample of 54 participants with atopic dermatitis. SCORAD index, laboratory tests, and local Ultraviolet index were assessed. RESULTS: The atopic dermatitis patients had serum 25(OH)D levels and mean UVI significantly higher than the control group. Immunoglobulin E and Ultraviolet index were associated with the SCORAD index. Skin type, age and Ultraviolet index were independent predictors of 25(OH)D. CONCLUSIONS: Although statistically significant, the different levels of 25(OH)D between the paired groups may be attributed to the higher mean Ultraviolet index in atopic dermatitis patients. Since Ultraviolet index is an independent predictor of SCORAD index and of 25(OH)D level, it may work as a confounding factor in studies involving atopic dermatitis and 25(OH)D and must be considered in this kind of research.
format Artigo
author Mesquita, Kleyton de Carvalho
Igreja, Ana Carolina de Souza Machado
Costa, Izelda Maria Carvalho
author_sort Mesquita, Kleyton de Carvalho
title Ultraviolet index : a light in atopic dermatitis and vitamin D research?
title_short Ultraviolet index : a light in atopic dermatitis and vitamin D research?
title_full Ultraviolet index : a light in atopic dermatitis and vitamin D research?
title_fullStr Ultraviolet index : a light in atopic dermatitis and vitamin D research?
title_full_unstemmed Ultraviolet index : a light in atopic dermatitis and vitamin D research?
title_sort ultraviolet index : a light in atopic dermatitis and vitamin d research?
publisher Sociedade Brasileira de Dermatologia
publishDate 2017
url http://repositorio.unb.br/handle/10482/30278
http://dx.doi.org/10.1590/abd1806-4841.20164337
_version_ 1641988084145848320
score 13.657419

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