Staff View: Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")

Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")

Physical training induces beneficial adaptation, whereas exhaustive exercises increase reactive oxygen-species generation, thereby causing oxidative damage in plasma and erythrocytes, fractions susceptible to lipid peroxidation. Pequi (Caryocar brasiliense Camb.) is a Brazilian Cerrado fruit contain...

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Main Authors:	Vilela, Ana Luísa Miranda, Akimoto, Arthur Kenji, Alves, Penha Cristina Zaidan, Pereira, Luiz Carlos da Silva, Guimarães, Maria de Nazaré Klautau, Grisolia, Cesar Koppe
Format:	Artigo
Language:	Inglês
Published:	Sociedade Brasileira de Genética 2018
Subjects:	Pequi Sangue - exame Antioxidantes
Online Access:	http://repositorio.unb.br/handle/10482/31829 http://dx.doi.org/10.1590/S1415-47572010005000022
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spelling	ir-10482-318292018-12-11T11:20:21Z Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia") Vilela, Ana Luísa Miranda Akimoto, Arthur Kenji Alves, Penha Cristina Zaidan Pereira, Luiz Carlos da Silva Guimarães, Maria de Nazaré Klautau Grisolia, Cesar Koppe Pequi Sangue - exame Antioxidantes Physical training induces beneficial adaptation, whereas exhaustive exercises increase reactive oxygen-species generation, thereby causing oxidative damage in plasma and erythrocytes, fractions susceptible to lipid peroxidation. Pequi (Caryocar brasiliense Camb.) is a Brazilian Cerrado fruit containing a carotenoid-rich oil. The aim was to investigate the effects of pequi-oil on exercise-induced oxidative damage in plasma and erythrocytes, after running in the same environment and undergoing weekly training under the same conditions as to type, intensity and length. Evaluations were accomplished after outdoor running on flat land before and after ingestion of 400 mg pequi-oil capsules for 14 days. Blood samples were taken after running and submitted to TBARS assay and erythrogram analysis. Haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms were priorly investigated, so as to estimate genetic influence The reduction in erythrocytes, hemoglobin and hematocrit after pequi-oil treatment was notably associated with higher plasma expansion. Except for MCHC (mean corpuscular hemoglobin concentration) and RDW (red cell distribution width), the results were influenced by the polymorphisms studied. The best response to pequi-oil was presented by MnSOD Val/Val, CAT AA or AT genotypes and the GPX1 Pro allele. The significantly lower RDW and higher MHCH values were related to pequi-oil protective effects. Pequi oil, besides possessing other nutritional properties, showed protective blood effects. 2018-05-11T14:12:56Z 2018-05-11T14:12:56Z 2010-03 Artigo MIRANDA-VILELA, Ana L. et al. Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners: influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia"). Genetics and Molecular Biology, São Paulo, v. 33, n. 2, p. 359-367, mar. 2010. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000200026&lng=en&nrm=iso>. Acesso em: 24 out. 2017. doi: http://dx.doi.org/10.1590/S1415-47572010005000022. http://repositorio.unb.br/handle/10482/31829 http://dx.doi.org/10.1590/S1415-47572010005000022 Inglês Acesso Aberto Genetics and Molecular Biology - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. (CC BY NC). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000200026&lng=en&nrm=iso. Acesso em: 24 out. 2017. application/pdf Sociedade Brasileira de Genética
institution	REPOSITORIO UNB
collection	REPOSITORIO UNB
language	Inglês
topic	Pequi Sangue - exame Antioxidantes
spellingShingle	Pequi Sangue - exame Antioxidantes Vilela, Ana Luísa Miranda Akimoto, Arthur Kenji Alves, Penha Cristina Zaidan Pereira, Luiz Carlos da Silva Guimarães, Maria de Nazaré Klautau Grisolia, Cesar Koppe Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")
description	Physical training induces beneficial adaptation, whereas exhaustive exercises increase reactive oxygen-species generation, thereby causing oxidative damage in plasma and erythrocytes, fractions susceptible to lipid peroxidation. Pequi (Caryocar brasiliense Camb.) is a Brazilian Cerrado fruit containing a carotenoid-rich oil. The aim was to investigate the effects of pequi-oil on exercise-induced oxidative damage in plasma and erythrocytes, after running in the same environment and undergoing weekly training under the same conditions as to type, intensity and length. Evaluations were accomplished after outdoor running on flat land before and after ingestion of 400 mg pequi-oil capsules for 14 days. Blood samples were taken after running and submitted to TBARS assay and erythrogram analysis. Haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms were priorly investigated, so as to estimate genetic influence The reduction in erythrocytes, hemoglobin and hematocrit after pequi-oil treatment was notably associated with higher plasma expansion. Except for MCHC (mean corpuscular hemoglobin concentration) and RDW (red cell distribution width), the results were influenced by the polymorphisms studied. The best response to pequi-oil was presented by MnSOD Val/Val, CAT AA or AT genotypes and the GPX1 Pro allele. The significantly lower RDW and higher MHCH values were related to pequi-oil protective effects. Pequi oil, besides possessing other nutritional properties, showed protective blood effects.
format	Artigo
author	Vilela, Ana Luísa Miranda Akimoto, Arthur Kenji Alves, Penha Cristina Zaidan Pereira, Luiz Carlos da Silva Guimarães, Maria de Nazaré Klautau Grisolia, Cesar Koppe
author_sort	Vilela, Ana Luísa Miranda
title	Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")
title_short	Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")
title_full	Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")
title_fullStr	Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")
title_full_unstemmed	Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")
title_sort	dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, mnsod (val9ala), cat (21a/t) and gpx1 (pro198leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")
publisher	Sociedade Brasileira de Genética
publishDate	2018
url	http://repositorio.unb.br/handle/10482/31829 http://dx.doi.org/10.1590/S1415-47572010005000022
_version_	1641987976591310848
score	13.657419

Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners : influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia ("sports anemia")

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