Impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults

Objective: Analyze the influence between the components of metabolic syndrome and the independent risk for cardiovascular disease (CVD) in the elderly. Methods: A descriptive cross-sectional study was carried out with 205 older adults from a primary healthcare unit of the Federal District, Brazil...

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Main Authors: Barbalho, Yuri Gustavo de Sousa, Stival, Marina Morato, Lima, Luciano Ramos de, Silva, Izabel Cristina Rodrigues da, Silva, Alessandro de Oliveira, Costa, Manoela Vieira Gomes da, Rehem, Tânia Cristina Morais Santa Bárbara, Funghetto, Silvana Schwerz
Format: Artigo
Language: Inglês
Published: Dove Press 2020
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Online Access: https://repositorio.unb.br/handle/10482/39658
https://doi.org/10.2147/CIA.S252589
https://orcid.org/0000-0002-5584-998X
https://orcid.org/0000-0001-6830-4914
https://orcid.org/0000-0002-2709-6335
https://orcid.org/0000-0002-6836-3583
https://orcid.org/0000-0003-3513-7034
https://orcid.org/0000-0002-2550-4307
https://orcid.org/0000-0002-9332-9029
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spelling ir-10482-396582021-04-23T14:16:12Z Impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults Barbalho, Yuri Gustavo de Sousa Stival, Marina Morato Lima, Luciano Ramos de Silva, Izabel Cristina Rodrigues da Silva, Alessandro de Oliveira Costa, Manoela Vieira Gomes da Rehem, Tânia Cristina Morais Santa Bárbara Funghetto, Silvana Schwerz Idosos Síndrome metabólica Sistema cardiovascular Envelhecimento Objective: Analyze the influence between the components of metabolic syndrome and the independent risk for cardiovascular disease (CVD) in the elderly. Methods: A descriptive cross-sectional study was carried out with 205 older adults from a primary healthcare unit of the Federal District, Brazil. The cardiovascular risk was determined by the Framingham Risk Score (FRS). The National Cholesterol Evaluation Program for Adult Treatment Panel III 2001 (NCEP-ATP III) criteria were considered to analyze metabolic syndrome (MS) diagnoses. Results: There was a strong association between MS and high cardiovascular risk (OR = 8.86). The univariate analysis main findings revealed that male gender, diabetes, smoking habit, systolic blood pressure, HDL level, high blood glucose, glycated hemoglobin, and LDL level were associated with high cardiovascular risk. FRS increases significantly with the presence of four or more MS components (by 30%, if 4 components are present, and by 40%, if 5 components) when compared with the presence of three or fewer components (P <0.001). A logistic regression analysis of high-risk predictors was described to reduce the effects of confounding and bias factors. Conclusion: The identification of MS associated with high FRS values represents a cascading of adverse effects on the population’s aging process. 2020-11-26T13:45:44Z 2020-11-26T13:45:44Z 2020-09-18 Artigo BARBALHO, Yuri Gustavo de Sousa et al. Impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults. Clinical Interventions in Aging, v. 15, p. 1691-1700, 2020. DOI: https://doi.org/10.2147/CIA.S252589. Disponível em: https://www.dovepress.com/impact-of-metabolic-syndrome-components-in-high-risk-cardiovascular-di-peer-reviewed-article-CIA. Acesso em: 26 nov. 2020. https://repositorio.unb.br/handle/10482/39658 https://doi.org/10.2147/CIA.S252589 https://orcid.org/0000-0002-5584-998X https://orcid.org/0000-0001-6830-4914 https://orcid.org/0000-0002-2709-6335 https://orcid.org/0000-0002-6836-3583 https://orcid.org/0000-0003-3513-7034 https://orcid.org/0000-0002-2550-4307 https://orcid.org/0000-0002-9332-9029 Inglês Acesso Aberto © 2020 Gustavo de Sousa Barbalho et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www. dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). application/pdf Dove Press
institution REPOSITORIO UNB
collection REPOSITORIO UNB
language Inglês
topic Idosos
Síndrome metabólica
Sistema cardiovascular
Envelhecimento
spellingShingle Idosos
Síndrome metabólica
Sistema cardiovascular
Envelhecimento
Barbalho, Yuri Gustavo de Sousa
Stival, Marina Morato
Lima, Luciano Ramos de
Silva, Izabel Cristina Rodrigues da
Silva, Alessandro de Oliveira
Costa, Manoela Vieira Gomes da
Rehem, Tânia Cristina Morais Santa Bárbara
Funghetto, Silvana Schwerz
Impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults
description Objective: Analyze the influence between the components of metabolic syndrome and the independent risk for cardiovascular disease (CVD) in the elderly. Methods: A descriptive cross-sectional study was carried out with 205 older adults from a primary healthcare unit of the Federal District, Brazil. The cardiovascular risk was determined by the Framingham Risk Score (FRS). The National Cholesterol Evaluation Program for Adult Treatment Panel III 2001 (NCEP-ATP III) criteria were considered to analyze metabolic syndrome (MS) diagnoses. Results: There was a strong association between MS and high cardiovascular risk (OR = 8.86). The univariate analysis main findings revealed that male gender, diabetes, smoking habit, systolic blood pressure, HDL level, high blood glucose, glycated hemoglobin, and LDL level were associated with high cardiovascular risk. FRS increases significantly with the presence of four or more MS components (by 30%, if 4 components are present, and by 40%, if 5 components) when compared with the presence of three or fewer components (P <0.001). A logistic regression analysis of high-risk predictors was described to reduce the effects of confounding and bias factors. Conclusion: The identification of MS associated with high FRS values represents a cascading of adverse effects on the population’s aging process.
format Artigo
author Barbalho, Yuri Gustavo de Sousa
Stival, Marina Morato
Lima, Luciano Ramos de
Silva, Izabel Cristina Rodrigues da
Silva, Alessandro de Oliveira
Costa, Manoela Vieira Gomes da
Rehem, Tânia Cristina Morais Santa Bárbara
Funghetto, Silvana Schwerz
author_sort Barbalho, Yuri Gustavo de Sousa
title Impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults
title_short Impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults
title_full Impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults
title_fullStr Impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults
title_full_unstemmed Impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults
title_sort impact of metabolic syndrome components in high-risk cardiovascular disease development in older adults
publisher Dove Press
publishDate 2020
url https://repositorio.unb.br/handle/10482/39658
https://doi.org/10.2147/CIA.S252589
https://orcid.org/0000-0002-5584-998X
https://orcid.org/0000-0001-6830-4914
https://orcid.org/0000-0002-2709-6335
https://orcid.org/0000-0002-6836-3583
https://orcid.org/0000-0003-3513-7034
https://orcid.org/0000-0002-2550-4307
https://orcid.org/0000-0002-9332-9029
_version_ 1710449533992828928
score 13.657419