Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge

In the absence of vaccines and effective antiviral drugs, control of the spread of coronavirus disease (Covid-19) relies mainly on the adequacy of public health resources and policies. Hence, failure to establish and implement scientifically reliable control measures may have a significant effect on...

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Main Author: Tosta, Carlos Eduardo
Format: Artigo
Language: Inglês
Published: Sociedade Brasileira de Medicina Tropical - SBMT 2020
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Online Access: https://repositorio.unb.br/handle/10482/39845
https://doi.org/10.1590/0037-8682-0669-2020
http://orcid.org/0000-0001-6586-2662
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spelling ir-10482-398452020-12-31T17:06:23Z Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge Tosta, Carlos Eduardo SARS-CoV-2 Covid-19 Infecção por coronavírus - transmissão Portador assintomático Transmissão aerotransportada In the absence of vaccines and effective antiviral drugs, control of the spread of coronavirus disease (Covid-19) relies mainly on the adequacy of public health resources and policies. Hence, failure to establish and implement scientifically reliable control measures may have a significant effect on the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, severity of the disease, and death toll. The average number of secondary transmissions from an infected person, or reproduction numbers (R0 and R), and the points at which the collective immunity begins to reduce the transmission of the infection, or herd immunity thresholds, are important epidemiological tools used in strategies of Covid-19 control, suppression, and mitigation. However, SARS-CoV-2 transmission through asymptomatic carriers and, possibly, aerosols, has been ignored, and this may affect the effectiveness of Covid-19 control strategies. Therefore, consideration of the two possible ways of transmission would substantially increase the values of reproduction numbers, but if estimates of the contingent of the population naturally resistant to the virus, plus those with pre-existing cross-immunity to SARS-CoV-2 were considered, the evaluation of herd immunity thresholds should reach their real and achievable levels. 2020-12-31T17:06:23Z 2020-12-31T17:06:23Z 2020 Artigo TOSTA, Eduardo. Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols: a major public health challenge. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 53, e20200669, 2020. DOI: https://doi.org/10.1590/0037-8682-0669-2020. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100212&lng=en&nrm=iso. Acesso em: 31 dez. 2020. Epub Dec 11, 2020. https://repositorio.unb.br/handle/10482/39845 https://doi.org/10.1590/0037-8682-0669-2020 http://orcid.org/0000-0001-6586-2662 Inglês Acesso Aberto OPEN ACCESS https://creativecommons.org/licenses/by/4.0/. application/pdf Sociedade Brasileira de Medicina Tropical - SBMT
institution REPOSITORIO UNB
collection REPOSITORIO UNB
language Inglês
topic SARS-CoV-2
Covid-19
Infecção por coronavírus - transmissão
Portador assintomático
Transmissão aerotransportada
spellingShingle SARS-CoV-2
Covid-19
Infecção por coronavírus - transmissão
Portador assintomático
Transmissão aerotransportada
Tosta, Carlos Eduardo
Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge
description In the absence of vaccines and effective antiviral drugs, control of the spread of coronavirus disease (Covid-19) relies mainly on the adequacy of public health resources and policies. Hence, failure to establish and implement scientifically reliable control measures may have a significant effect on the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, severity of the disease, and death toll. The average number of secondary transmissions from an infected person, or reproduction numbers (R0 and R), and the points at which the collective immunity begins to reduce the transmission of the infection, or herd immunity thresholds, are important epidemiological tools used in strategies of Covid-19 control, suppression, and mitigation. However, SARS-CoV-2 transmission through asymptomatic carriers and, possibly, aerosols, has been ignored, and this may affect the effectiveness of Covid-19 control strategies. Therefore, consideration of the two possible ways of transmission would substantially increase the values of reproduction numbers, but if estimates of the contingent of the population naturally resistant to the virus, plus those with pre-existing cross-immunity to SARS-CoV-2 were considered, the evaluation of herd immunity thresholds should reach their real and achievable levels.
format Artigo
author Tosta, Carlos Eduardo
author_sort Tosta, Carlos Eduardo
title Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge
title_short Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge
title_full Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge
title_fullStr Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge
title_full_unstemmed Transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge
title_sort transmission of severe acute respiratory syndrome coronavirus 2 through asymptomatic carriers and aerosols : a major public health challenge
publisher Sociedade Brasileira de Medicina Tropical - SBMT
publishDate 2020
url https://repositorio.unb.br/handle/10482/39845
https://doi.org/10.1590/0037-8682-0669-2020
http://orcid.org/0000-0001-6586-2662
_version_ 1688329556283359232
score 13.657419