Melittin sensitizes skin squamous carcinoma cells to 5-fluorouracil by affecting cell proliferation and survival

Combined 5-fluorouracil (5-FU) and melittin (MEL) is believed to enhance cytotoxic effects on skin squamous cell carcinoma (SCC). However, the rationale underlying cytotoxicity is fundamentally important for a proper design of combination chemotherapy, and to provide translational insights for futur...

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Main Authors: Ombredane, Alicia Simalie, Andrade, Laise Rodrigues de, Bonadio, Raphael Severino, Pinheiro, Willie Oliveira, Azevedo, Ricardo Bentes de, Joanitti, Graziella Anselmo
Format: Artigo
Language: Inglês
Published: John Wiley & Sons Ltd 2021
Subjects:
Online Access: https://repositorio.unb.br/handle/10482/41115
https://doi.org/10.1111/exd.14289
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