Role of phosphodiesterase 5 in cardiovascular pathophysiology in spontaneously hypertensive rats

The aim of this study was to investigate the impact of chronic phosphodiesterase type 5A inhibition (PDE5Ai) by sildenafil in different stages of development in a model of essential hypertension. For this purpose, male spontaneously hypertensive rats (SHRs) were chronically treated with PDE5A inhibi...

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Main Author: SILVA, José Jairo Teixeira da
Other Authors: DUARTE, Glória Isolina Boente Pinto
Format: doctoralThesis
Language: por
Published: Universidade Federal de Pernambuco 2020
Subjects:
Online Access: https://repositorio.ufpe.br/handle/123456789/36896
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