Development and characterization of recombinant antibody Fragments that recognize and neutralize in vitro Stx2 toxin from shiga toxin-producing escherichia coli
Background: Stx toxin is a member of the AB5 family of bacterial toxins: the active A subunit has N-glycosidase activity against 28S rRNA, resulting in inhibition of protein synthesis in eukaryotic cells, and the pentamer ligand B subunits (StxB) bind to globotria(tetra)osylceramide receptors (Gb3/G...
| Main Authors: | Luz, Daniela, Chen, Gang, Maranhão, Andrea Queiroz, Rocha, Leticia Barboza, Sidhu, Sachdev, Piazza, Roxane Maria Fontes |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Plos One
2017
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| Subjects: | |
| Online Access: |
http://repositorio.unb.br/handle/10482/22422 http://dx.doi.org/10.1371/journal.pone.0120481 |
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