Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil

We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most p...

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Main Authors: Cruz, Márcio R, Cerqueira, Daniela M, Cruz, Waldenor B, Camara, Geni NL, Brígido, Marcelo de Macedo, Silva, Evandro O, Carvalho, Luciano GS, Martins, Cláudia RF
Format: Artigo
Language: English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2017
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Online Access: http://repositorio.unb.br/handle/10482/26144
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spelling ir-10482-261442019-03-28T14:05:13Z Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil Cruz, Márcio R Cerqueira, Daniela M Cruz, Waldenor B Camara, Geni NL Brígido, Marcelo de Macedo Silva, Evandro O Carvalho, Luciano GS Martins, Cláudia RF human papillomavirus type 16 variants Federal District Brazil We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma. 2017-12-07T04:39:11Z 2017-12-07T04:39:11Z 2004 Artigo Mem. Inst. Oswaldo Cruz,v.99,n.3,p.281-282,2004 0074-0276 http://repositorio.unb.br/handle/10482/26144 10.1590/S0074-02762004000300007 en Acesso Aberto application/pdf Instituto Oswaldo Cruz, Ministério da Saúde http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300007&lng=en&nrm=iso http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0074-02762004000300007&lng=en&nrm=iso http://www.scielo.br/scielo.php?script=sci_pdf&pid=S0074-02762004000300007&lng=en&nrm=iso
institution REPOSITORIO UNB
collection REPOSITORIO UNB
language English
topic human papillomavirus type 16
variants
Federal District
Brazil
spellingShingle human papillomavirus type 16
variants
Federal District
Brazil
Cruz, Márcio R
Cerqueira, Daniela M
Cruz, Waldenor B
Camara, Geni NL
Brígido, Marcelo de Macedo
Silva, Evandro O
Carvalho, Luciano GS
Martins, Cláudia RF
Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
description We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.
format Artigo
author Cruz, Márcio R
Cerqueira, Daniela M
Cruz, Waldenor B
Camara, Geni NL
Brígido, Marcelo de Macedo
Silva, Evandro O
Carvalho, Luciano GS
Martins, Cláudia RF
author_sort Cruz, Márcio R
title Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_short Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_full Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_fullStr Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_full_unstemmed Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
title_sort prevalence of human papillomavirus type 16 variants in the federal district, central brazil
publisher Instituto Oswaldo Cruz, Ministério da Saúde
publishDate 2017
url http://repositorio.unb.br/handle/10482/26144
_version_ 1641988419045294080
score 13.657419