Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most p...
Main Authors: | Cruz, Márcio R, Cerqueira, Daniela M, Cruz, Waldenor B, Camara, Geni NL, Brígido, Marcelo de Macedo, Silva, Evandro O, Carvalho, Luciano GS, Martins, Cláudia RF |
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Language: | English |
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Instituto Oswaldo Cruz, Ministério da Saúde
2017
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http://repositorio.unb.br/handle/10482/26144 |
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ir-10482-261442019-03-28T14:05:13Z Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil Cruz, Márcio R Cerqueira, Daniela M Cruz, Waldenor B Camara, Geni NL Brígido, Marcelo de Macedo Silva, Evandro O Carvalho, Luciano GS Martins, Cláudia RF human papillomavirus type 16 variants Federal District Brazil We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma. 2017-12-07T04:39:11Z 2017-12-07T04:39:11Z 2004 Artigo Mem. Inst. Oswaldo Cruz,v.99,n.3,p.281-282,2004 0074-0276 http://repositorio.unb.br/handle/10482/26144 10.1590/S0074-02762004000300007 en Acesso Aberto application/pdf Instituto Oswaldo Cruz, Ministério da Saúde http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300007&lng=en&nrm=iso http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0074-02762004000300007&lng=en&nrm=iso http://www.scielo.br/scielo.php?script=sci_pdf&pid=S0074-02762004000300007&lng=en&nrm=iso |
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human papillomavirus type 16 variants Federal District Brazil |
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human papillomavirus type 16 variants Federal District Brazil Cruz, Márcio R Cerqueira, Daniela M Cruz, Waldenor B Camara, Geni NL Brígido, Marcelo de Macedo Silva, Evandro O Carvalho, Luciano GS Martins, Cláudia RF Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
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We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma. |
format |
Artigo |
author |
Cruz, Márcio R Cerqueira, Daniela M Cruz, Waldenor B Camara, Geni NL Brígido, Marcelo de Macedo Silva, Evandro O Carvalho, Luciano GS Martins, Cláudia RF |
author_sort |
Cruz, Márcio R |
title |
Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
title_short |
Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
title_full |
Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
title_fullStr |
Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
title_full_unstemmed |
Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
title_sort |
prevalence of human papillomavirus type 16 variants in the federal district, central brazil |
publisher |
Instituto Oswaldo Cruz, Ministério da Saúde |
publishDate |
2017 |
url |
http://repositorio.unb.br/handle/10482/26144 |
_version_ |
1641988419045294080 |
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13.657419 |