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Impact of a chromosome X STR Decaplex in deficiency paternity cases

Deficiency paternity cases, characterized by the absence of the alleged father, are a challenge for forensic genetics. Here we present four cases with a female child and a deceased alleged father in which the analysis of a set of 21 or 22 autosomal STRs (AS STRs) produced results within a range of d...

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Main Authors: Trindade Filho, Aluisio, Ferreira, Samuel, Oliveira, Silviene Fabiana de
Format: Artigo
Language: English
Published: Sociedade Brasileira de Genética 2017
Subjects:
Genética forense
Paternidade
Online Access: http://repositorio.unb.br/handle/10482/28964
https://dx.doi.org/10.1590/S1415-47572013000400008
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spelling ir-10482-289642020-12-14T17:48:02Z Impact of a chromosome X STR Decaplex in deficiency paternity cases Trindade Filho, Aluisio Ferreira, Samuel Oliveira, Silviene Fabiana de Genética forense Paternidade Deficiency paternity cases, characterized by the absence of the alleged father, are a challenge for forensic genetics. Here we present four cases with a female child and a deceased alleged father in which the analysis of a set of 21 or 22 autosomal STRs (AS STRs) produced results within a range of doubt when genotyping relatives of the alleged father. Aiming to increase the Paternity Index (PI) and obtain more reliable results, a set of 10 X-linked STR markers, developed by the Spanish and Portuguese Group of the International Society for Forensic Genetics (ISFG), was then added. Statistical analysis substantially shifted the results towards the alleged fatherhood in all four cases, with more dramatic changes when the supposed half-sister and respective mother were the relatives tested. 2017-12-07T05:03:45Z 2017-12-07T05:03:45Z 2013 Artigo TRINDADE FILHO, Aluisio; FERREIRA, Samuel; OLIVEIRA, Silviene Fabiana de. Impact of a chromosome X STR Decaplex in deficiency paternity cases. Genetics and Molecular Biology, São Paulo, v. 36, n. 4, p. 507-510, 2013. DOI: https://doi.org/10.1590/S1415-47572013000400008. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400008&lng=en&nrm=iso. Acesso em: 04 dez. 2020. http://repositorio.unb.br/handle/10482/28964 https://dx.doi.org/10.1590/S1415-47572013000400008 en Acesso Aberto Genetics and Molecular Biology - Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (CC BY NC 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400008&lng=en&nrm=iso. Acesso em: 04 dez. 2020. application/pdf Sociedade Brasileira de Genética
institution REPOSITORIO UNB
collection REPOSITORIO UNB
language English
topic Genética forense
Paternidade
spellingShingle Genética forense
Paternidade
Trindade Filho, Aluisio
Ferreira, Samuel
Oliveira, Silviene Fabiana de
Impact of a chromosome X STR Decaplex in deficiency paternity cases
description Deficiency paternity cases, characterized by the absence of the alleged father, are a challenge for forensic genetics. Here we present four cases with a female child and a deceased alleged father in which the analysis of a set of 21 or 22 autosomal STRs (AS STRs) produced results within a range of doubt when genotyping relatives of the alleged father. Aiming to increase the Paternity Index (PI) and obtain more reliable results, a set of 10 X-linked STR markers, developed by the Spanish and Portuguese Group of the International Society for Forensic Genetics (ISFG), was then added. Statistical analysis substantially shifted the results towards the alleged fatherhood in all four cases, with more dramatic changes when the supposed half-sister and respective mother were the relatives tested.
format Artigo
author Trindade Filho, Aluisio
Ferreira, Samuel
Oliveira, Silviene Fabiana de
author_sort Trindade Filho, Aluisio
title Impact of a chromosome X STR Decaplex in deficiency paternity cases
title_short Impact of a chromosome X STR Decaplex in deficiency paternity cases
title_full Impact of a chromosome X STR Decaplex in deficiency paternity cases
title_fullStr Impact of a chromosome X STR Decaplex in deficiency paternity cases
title_full_unstemmed Impact of a chromosome X STR Decaplex in deficiency paternity cases
title_sort impact of a chromosome x str decaplex in deficiency paternity cases
publisher Sociedade Brasileira de Genética
publishDate 2017
url http://repositorio.unb.br/handle/10482/28964
https://dx.doi.org/10.1590/S1415-47572013000400008
_version_ 1686784730112983040
score 13.657419

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