Catalyzed and non-catalyzed synthesis of bioactive monastrol

The bioactive 3,4-dihydropyrimidin-2(1H)-thione derivative known as Monastrol was synthesized under catalyzed and non-catalyzed conditions through the Biginelli multicomponent reaction under solvent-free conditions. The use of two Lewis acids (FeCl3 and CuCl2) and two Brønsted acids (HCl and CF3COOH...

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Main Authors: Alvim, Haline Gerica de Oliveira, Corrêa, José Raimundo, Machado, Taynara Rezende, Silva, Wender Alves da, Neto, Brenno A.
Format: Artigo
Language: English
Published: Sociedade Brasileira de Química 2017
Subjects:
Online Access: http://repositorio.unb.br/handle/10482/29152
https://dx.doi.org/10.5935/0100-4042.20140266
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