Depression and anxiety in patients with multiple sclerosis treated with interferon-beta or fingolimod : role of indoleamine 2,3-dioxygenase and pro-inflammatory cytokines
Depression/anxiety (D/A) occurs in up to 50% of multiple sclerosis (MS) patients. Proinflammatory cytokines induce classical symptoms of depression. Activation of the inflammatory response also triggers production of indoleamine 2,3-dioxygenase (IDO), which catabolizes tryptophan, the amino acid p...
| Main Authors: | Tauil, Carlos Bernardo, Lima, Amanda D. da Rocha, Ferrari, Breno B., Silva, Veronica A. G. da, Moraes, Adriel S., Silva, Flavia M. da, Silva, Cesar A. Melo, Farias, Alessandro S., Brandão, Carlos O., Santos, Leonilda M. B. dos, Santos Neto, Leopoldo Luiz dos |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier Inc.
2020
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| Subjects: | |
| Online Access: |
https://repositorio.unb.br/handle/10482/39610 https://doi.org/10.1016/j.bbih.2020.100162 |
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